Title : Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).

Pub. Date : 2009 Jun

PMID : 18563554






2 Functional Relationships(s)
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1 Indeed, two recent studies demonstrated that anchorage-dependent growth of some human breast cancer cell lines is impaired by cyclopamine, a potent hedgehog signaling antagonist targeting the Smoothened (SMO) protein. cyclopamine smoothened, frizzled class receptor Homo sapiens
2 Indeed, two recent studies demonstrated that anchorage-dependent growth of some human breast cancer cell lines is impaired by cyclopamine, a potent hedgehog signaling antagonist targeting the Smoothened (SMO) protein. cyclopamine smoothened, frizzled class receptor Homo sapiens