Pub. Date : 2008 Aug
PMID : 18559982
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | Free radical production was unchanged in the NADPH oxidase knockout but much decreased in the iNOS knockout mice, suggesting a role for iNOS in free radical production. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | Free radical production was unchanged in the NADPH oxidase knockout but much decreased in the iNOS knockout mice, suggesting a role for iNOS in free radical production. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |
| 4 | Free radical production was unchanged in the NADPH oxidase knockout but much decreased in the iNOS knockout mice, suggesting a role for iNOS in free radical production. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |
| 5 | Free radical production was unchanged in the NADPH oxidase knockout but much decreased in the iNOS knockout mice, suggesting a role for iNOS in free radical production. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |
| 6 | Taken together, our data demonstrate that acetone administration, a model of ketosis, can lead to protein oxidation and lipid peroxidation through a free radical-dependent mechanism driven mainly by iNOS overexpression. | Free Radicals | nitric oxide synthase 2, inducible | Mus musculus |