Pub. Date : 2008 Jun 24
PMID : 18559696
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans. | aliskiren | renin | Homo sapiens |
2 | We predicted that blockade with the direct oral renin inhibitor aliskiren would produce renal vascular responses exceeding those induced by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. | aliskiren | renin | Homo sapiens |
3 | CONCLUSIONS: Renal vasodilation in healthy people with the potent renin inhibitor aliskiren exceeded responses seen previously with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. | aliskiren | renin | Homo sapiens |
4 | These results indicate that aliskiren may provide more complete and thus more effective blockade of the renin-angiotensin system. | aliskiren | renin | Homo sapiens |