Title : Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans.

Pub. Date : 2008 Jun 24

PMID : 18559696






4 Functional Relationships(s)
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1 Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans. aliskiren renin Homo sapiens
2 We predicted that blockade with the direct oral renin inhibitor aliskiren would produce renal vascular responses exceeding those induced by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. aliskiren renin Homo sapiens
3 CONCLUSIONS: Renal vasodilation in healthy people with the potent renin inhibitor aliskiren exceeded responses seen previously with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. aliskiren renin Homo sapiens
4 These results indicate that aliskiren may provide more complete and thus more effective blockade of the renin-angiotensin system. aliskiren renin Homo sapiens