Title : Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage.

Pub. Date : 2008 Jun 15

PMID : 18559532






1 Functional Relationships(s)
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1 In this study, we show that Tax sensitizes p53-mutant cells to a broad range of DNA-damaging agents, including mitomycin C, a bifunctional alkylator, etoposide, a topoisomerase II drug, and UV light, but not ionizing radiation, a double-strand break agent, or vinblastine, a tubulin poison. Mitomycin tumor protein p53 Homo sapiens