Title : Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats.

Pub. Date : 2008 Jul 17

PMID : 18554810






4 Functional Relationships(s)
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1 administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihydroxyphenylacetic acid, DOPAC) in the nucleus accumbens (NA) and striatum (ST) in ovariectomized (OVX) female Sprague-Dawley rats with E(2)-priming. 3,4-Dihydroxyphenylacetic Acid CART prepropeptide Rattus norvegicus
2 administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihydroxyphenylacetic acid, DOPAC) in the nucleus accumbens (NA) and striatum (ST) in ovariectomized (OVX) female Sprague-Dawley rats with E(2)-priming. 3,4-Dihydroxyphenylacetic Acid CART prepropeptide Rattus norvegicus
3 This stimulation of NA and ST DOPAC contents by CART peptide was found in OVX+E(2) female rats, but not in OVX only female rats, suggesting E(2) is an important factor in modulating the stimulatory effect of CART in the regulation of NA and ST DOPAC contents. 3,4-Dihydroxyphenylacetic Acid CART prepropeptide Rattus norvegicus
4 This stimulation of NA and ST DOPAC contents by CART peptide was found in OVX+E(2) female rats, but not in OVX only female rats, suggesting E(2) is an important factor in modulating the stimulatory effect of CART in the regulation of NA and ST DOPAC contents. 3,4-Dihydroxyphenylacetic Acid CART prepropeptide Rattus norvegicus