Title : Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes.

Pub. Date : 2008 Jun 12

PMID : 18549505






1 Functional Relationships(s)
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1 Curcumin and resveratrol treatment inhibited NF-kappaB activation and resulted in a reduction of TNF-alpha, IL-1beta, IL-6, and COX-2 gene expression (IC50 = 2 muM) and a reduction of secreted IL-6 and PGE2 (IC50 ~ 20 muM). Curcumin mitochondrially encoded cytochrome c oxidase II Homo sapiens