Title : The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

Pub. Date : 2008 Jun 17

PMID : 18544649






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In fibroblasts, which express p110beta but not p110gamma, p110beta mediated Akt activation by the GPCR ligands stromal cell-derived factor, sphingosine-1-phosphate, and lysophosphatidic acid but not by the Tyr kinase ligands PDGF, insulin, and insulin-like growth factor 1. lysophosphatidic acid thymoma viral proto-oncogene 1 Mus musculus