Title : Is testosterone and estrogen priming prior to clonidine useful in the evaluation of the growth hormone status of short peripubertal children?

Pub. Date : 2008 Mar

PMID : 18540253






4 Functional Relationships(s)
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1 RESULTS: Twenty-one of 39 children (53.8%) increased their GH response to a level of >10 microg/l following priming with gonadal steroids. Steroids growth hormone 1 Homo sapiens
2 CONCLUSIONS: Priming with gonadal steroids significantly improves GH secretion following GH stimulation with clonidine and diminishes the possibility of a false diagnosis of GH deficiency. Steroids growth hormone 1 Homo sapiens
3 CONCLUSIONS: Priming with gonadal steroids significantly improves GH secretion following GH stimulation with clonidine and diminishes the possibility of a false diagnosis of GH deficiency. Steroids growth hormone 1 Homo sapiens
4 Gonadal steroid priming should therefore be considered in the evaluation of the GH status of short children close to or during the early stages of puberty. Steroids growth hormone 1 Homo sapiens