Title : Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model.

Pub. Date : 2009 Jul-Aug

PMID : 18534874






1 Functional Relationships(s)
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1 PURPOSE: Sunitinib malate (Pfizer, Inc.) is a multitargeted kinase inhibitor that inhibits vascular endothelial growth factor (VEGF) receptor (R)-1, 2 and 3, platelet-derived growth factor receptors (PDGFR)-alpha and beta, Flt3, RET, and Kit. Sunitinib ret proto-oncogene Homo sapiens