Title : Novel binding mode of the acidic CYP2D6 substrates pactimibe and its metabolite R-125528.

Pub. Date : 2008 Sep

PMID : 18524873






1 Functional Relationships(s)
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1 The effect of the N-alkyl chain length of pactimibe analogs on their CYP2D6 metabolic stability was plausibly explained by the docking model. pactimibe cytochrome P450 family 2 subfamily D member 6 Homo sapiens