Pub. Date : 2008 Oct
PMID : 18521569
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | "Host tissue damage" signal ATP impairs IL-12 and IFNgamma secretion in LPS stimulated whole human blood. | Adenosine Triphosphate | interferon gamma | Homo sapiens |
| 2 | ADP, ATPgammaS, BzATP, and CV1808, but not UTP displayed IL-12(p70) and IFNgamma reducing effect similar to ATP. | Adenosine Triphosphate | interferon gamma | Homo sapiens |
| 3 | CONCLUSIONS: ATP and ADP at high-micromolar concentrations reduce secretion of the main Th1 cytokines TNFalpha, IL-12(p70) and IFNgamma in LPS stimulated human blood. | Adenosine Triphosphate | interferon gamma | Homo sapiens |