Title : G proteins coupled to phospholipase C: molecular targets of long-term ethanol exposure.

Pub. Date : 1991 Jun

PMID : 1851210






1 Functional Relationships(s)
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1 Ethanol exposure reduced guanosine 5"-O-(3-thiotriphosphate) [GTP(S)]- and, to a lesser extent, NaF/AlCl3-stimulated phosphoinositide hydrolysis, whereas it had no effect on the enzymatic activity of a phosphatidylinositol 4,5-bisphosphate-specific phospholipase C. [3H]Bradykinin binding in the absence of GTP(S) was not influenced by ethanol exposure. Phosphatidylinositols C-X-C motif chemokine ligand 8 Homo sapiens