Title : Successive copper(I)-catalyzed cross-couplings in one pot: a novel and efficient starting point for synthesis of carbapenems.

Pub. Date : 2008 Jul 3

PMID : 18510330






1 Functional Relationships(s)
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1 The method involves highly selective intramolecular coupling of lactam and dihaloalkene using 2,2"-bipyridine as a ligand, followed by intermolecular C-S formation in the presence of another ligand (1,10-phenanthroline, PPh 3) and mercaptan. 1,10-phenanthroline caveolin 1 Homo sapiens