Title : Critical role of cysteine residue 81 of macrophage migration inhibitory factor (MIF) in MIF-induced inhibition of p53 activity.

Pub. Date : 2008 Jul 18

PMID : 18502749






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Critical role of cysteine residue 81 of macrophage migration inhibitory factor (MIF) in MIF-induced inhibition of p53 activity. Cysteine tumor protein p53 Homo sapiens
2 This association was significantly reduced by a C81S mutation but not C57S or C60S mutations, suggesting that Cys(81) is essential for the in vivo association between MIF and p53. Cysteine tumor protein p53 Homo sapiens
3 This association also depended on Cys(242) (and, to some extent, on Cys(238)) within the central DNA binding domain of p53. Cysteine tumor protein p53 Homo sapiens
4 This association also depended on Cys(242) (and, to some extent, on Cys(238)) within the central DNA binding domain of p53. Cysteine tumor protein p53 Homo sapiens