Title : Inhibitory effects of a dietary phytochemical 3,3'-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats.

Pub. Date : 2008 Jul

PMID : 18486294






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Evaluation of the effects of co-treatment of rats with PB and DIM by a full factorial ANOVA showed that DIM decreased the PB-induced CYP2B1 and CYP2B2 mRNA expression levels, and the rates of 2- and 4-hydroxylation of E2, and total E2 metabolite formation. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus
2 Evaluation of the effects of co-treatment of rats with PB and DIM by a full factorial ANOVA showed that DIM decreased the PB-induced CYP2B1 and CYP2B2 mRNA expression levels, and the rates of 2- and 4-hydroxylation of E2, and total E2 metabolite formation. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus