Title : TNF-alpha induces two distinct caspase-8 activation pathways.

Pub. Date : 2008 May 16

PMID : 18485876






1 Functional Relationships(s)
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1 The inflammatory response of mammalian cells to TNF-alpha can be switched to apoptosis either by cotreatment with a protein synthesis inhibitor, cycloheximide, or Smac mimetic, a small molecule mimic of Smac/Diablo protein. Cycloheximide tumor necrosis factor Homo sapiens