Title : Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.

Pub. Date : 2008 Aug 1

PMID : 18480048






3 Functional Relationships(s)
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1 Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125. pyrazolanthrone TTK protein kinase Homo sapiens
2 To gain insights into the molecular mechanism of Mps1 inhibition by small molecules, we determined the x-ray structure of Mps1, both alone and in complex with the ATP-competitive inhibitor SP600125. pyrazolanthrone TTK protein kinase Homo sapiens
3 To gain insights into the molecular mechanism of Mps1 inhibition by small molecules, we determined the x-ray structure of Mps1, both alone and in complex with the ATP-competitive inhibitor SP600125. pyrazolanthrone TTK protein kinase Homo sapiens