Title : Carbonic Anhydrase Interaction With Lipothioars Enites: A Novel Class of Isozymes I and II Inhibitors.

Pub. Date : 1996

PMID : 18475756






1 Functional Relationships(s)
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1 Together with the arsonolipids previously investigated, the active compounds of this series - the "lipothioarsenites"- constitute a novel class of CA inhibitors that bind to the metal ion within the enzyme active site, as proved by changes in the electronic spectra of adducts of such inhibitors with Co(II)CA. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens