Pub. Date : 2008 Jul
PMID : 18473128
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species. | Reactive Oxygen Species | thrombopoietin | Homo sapiens |
| 2 | Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species. | Reactive Oxygen Species | thrombopoietin | Homo sapiens |
| 3 | In this study, we explored the mechanisms and found that TPO-induced mitochondrial reactive oxygen species (ROS) played a crucial role in stabilization of HIF-1. | Reactive Oxygen Species | thrombopoietin | Homo sapiens |
| 4 | In this study, we explored the mechanisms and found that TPO-induced mitochondrial reactive oxygen species (ROS) played a crucial role in stabilization of HIF-1. | Reactive Oxygen Species | thrombopoietin | Homo sapiens |
| 5 | Both ROS scavengers and inhibitors of mitochondrial electron transport completely blocked HIF-1alpha induction by TPO in UT-7/TPO cells and in primary immature mouse bone marrow cells. | Reactive Oxygen Species | thrombopoietin | Homo sapiens |