Pub. Date : 2008 Aug
PMID : 18470848
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enhanced iodide sequestration by 3-biphenyl-5,6-dihydroimidazo[2,1-b]thiazole in sodium/iodide symporter (NIS)-expressing cells. | Iodides | solute carrier family 5 member 5 | Homo sapiens |
| 2 | Enhanced iodide sequestration by 3-biphenyl-5,6-dihydroimidazo[2,1-b]thiazole in sodium/iodide symporter (NIS)-expressing cells. | Iodides | solute carrier family 5 member 5 | Homo sapiens |
| 3 | The ability of the sodium/iodide symporter (NIS) to take up iodide has long provided the basis for cytoreductive gene therapy and cancer treatment with radioiodide. | Iodides | solute carrier family 5 member 5 | Homo sapiens |
| 4 | We identified and characterized a small organic molecule capable of increasing iodide retention in HEK293 cells permanently transfected with human NIS cDNA (hNIS-HEK293) and in the rat thyroid-derived cell line FRTL-5. | Iodides | solute carrier family 5 member 5 | Homo sapiens |
| 5 | This new compound is not only an attractive chemical tool to investigate the mechanisms of iodide flux at the cellular level, but also opens promising perspectives in the treatment of cancer after NIS gene transfer. | Iodides | solute carrier family 5 member 5 | Homo sapiens |