Pub. Date : 2008 Sep
PMID : 18464797
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The exposure of calreticulin (CRT) on the plasma membrane can precede anthracycline-induced apoptosis and is required for cell death to be perceived as immunogenic. | Anthracyclines | calreticulin | Homo sapiens |
| 2 | The exposure of calreticulin (CRT) on the plasma membrane can precede anthracycline-induced apoptosis and is required for cell death to be perceived as immunogenic. | Anthracyclines | calreticulin | Homo sapiens |
| 3 | The knockout and knockdown of CRT or ERp57 inhibited the anthracycline-induced translocation of ERp57 or CRT, respectively. | Anthracyclines | calreticulin | Homo sapiens |
| 4 | The knockout and knockdown of CRT or ERp57 inhibited the anthracycline-induced translocation of ERp57 or CRT, respectively. | Anthracyclines | calreticulin | Homo sapiens |
| 5 | These results indicate that tumors that possess an intrinsic defect in the CRT-translocating machinery become resistant to anthracycline chemotherapy due to their incapacity to elicit an anti-cancer immune response. | Anthracyclines | calreticulin | Homo sapiens |