Pub. Date : 1991
PMID : 1846237
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Participation of growth factors and intracellular cAMP in direct antiproliferative action of interferon alpha (IFN-alpha) was investigated in PC-3 human prostate carcinoma cell line. | Cyclic AMP | interferon alpha 1 | Homo sapiens |
| 2 | On the other hand, IFN-alpha increased intracellular cAMP concentration about 20-fold. | Cyclic AMP | interferon alpha 1 | Homo sapiens |
| 3 | These indicated that direct antiproliferative effect of IFN-alpha on PC-3 cells was at least partly mediated by cAMP, and that neither growth factors nor a growth inhibitor participated in the action of IFN-alpha. | Cyclic AMP | interferon alpha 1 | Homo sapiens |