Title : N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.

Pub. Date : 2008 Aug

PMID : 18460644






3 Functional Relationships(s)
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1 Further development of nAChR antagonists that inhibit nicotine-evoked DA release and penetrate brain to antagonize DA-mediated locomotor stimulant effects of nicotine as novel treatments for nicotine addiction is warranted. Nicotine cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus
2 Further development of nAChR antagonists that inhibit nicotine-evoked DA release and penetrate brain to antagonize DA-mediated locomotor stimulant effects of nicotine as novel treatments for nicotine addiction is warranted. Nicotine cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus
3 Further development of nAChR antagonists that inhibit nicotine-evoked DA release and penetrate brain to antagonize DA-mediated locomotor stimulant effects of nicotine as novel treatments for nicotine addiction is warranted. Nicotine cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus