Pub. Date : 2008 Jul
PMID : 18460571
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The insulin-sensitizing effect of rosiglitazone in type 2 diabetes mellitus patients does not require improved in vivo muscle mitochondrial function. | Rosiglitazone | insulin | Homo sapiens |
| 2 | AIMS: Our objective was to investigate whether improved in vivo mitochondrial function in skeletal muscle and intramyocellular lipids (IMCLs) contribute to the insulin-sensitizing effect of rosiglitazone. | Rosiglitazone | insulin | Homo sapiens |
| 3 | RESULTS: Insulin sensitivity improved after rosiglitazone (glucose infusion rate: 19.9 +/- 2.8 to 24.8 +/- 2.1 micromol/kg.min; P < 0.05). | Rosiglitazone | insulin | Homo sapiens |
| 4 | CONCLUSION: The rosiglitazone-enhanced insulin sensitivity does not require improved muscular mitochondrial function. | Rosiglitazone | insulin | Homo sapiens |