Title : Plasmin induces degradation and dysfunction of laminin 332 (laminin 5) and impaired assembly of basement membrane at the dermal-epidermal junction.

Pub. Date : 2008 Jul

PMID : 18460030






1 Functional Relationships(s)
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1 The addition of aprotinin, a serine proteinase inhibitor, and tranexamic acid, a uPA-plasmin inhibitor, inhibited the plasmin-induced impairment of BM assembly and facilitated BM reorganization, thereby improving the epidermal structure. Tranexamic Acid plasminogen activator, urokinase Homo sapiens