Title : Activation of constitutive androstane receptor under the effect of hepatocarcinogenic aminoazo dyes in mouse and rat liver.

Pub. Date : 2007 Sep

PMID : 18457031






1 Functional Relationships(s)
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1 Selective increase of DNA-binding activity of constitutive androstane receptor was detected in rat and mouse liver in response to aminoazo dyes exhibiting hepatocarcinogenic activity for these species (ortho-aminoazotoluene for mice and 3"-methyl-4-dimethylaminobenzene for rats). o-Aminoazotoluene nuclear receptor subfamily 1, group I, member 3 Rattus norvegicus