Title : Spectroscopic investigation on the binding of bioactive pyridazinone derivative to human serum albumin and molecular modeling.

Pub. Date : 2008 Aug 1

PMID : 18456467






2 Functional Relationships(s)
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1 Spectroscopic investigation on the binding of bioactive pyridazinone derivative to human serum albumin and molecular modeling. 2-phenyl-3(2H)-pyridazinone albumin Homo sapiens
2 The interaction between a novel promising pyridazinone derivative (5-chloro-2-nitro-N-(4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)benzamide (CNPB)) and human serum albumin (HSA) under physiological conditions has been investigated systematically by fluorescence spectroscopy, UV absorption spectroscopy, circular dichroism (CD) and molecular modeling. 2-phenyl-3(2H)-pyridazinone albumin Homo sapiens