Title : Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex.

Pub. Date : 2008 Jun

PMID : 18455431






1 Functional Relationships(s)
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1 In the presence of NMDA, a low concentration of the 5-HT(1A) agonist 8-OH-DPAT substantially reduced the number of spikes, and a low concentration of the 5-HT(2A/C) agonist alpha-Me-5HT significantly enhanced it, while both agonists were ineffective when applied alone. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Homo sapiens