Title : Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage.

Pub. Date : 2008 May

PMID : 18455424






1 Functional Relationships(s)
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1 In the present study, we show that bromocriptine upregulates the expression and activity of NQO1, attenuates the increase in the protein-bound quinone in H(2)O(2)-treated PC12 cells, and protects PC12 cells against oxidative damage. quinone NAD(P)H quinone dehydrogenase 1 Rattus norvegicus