Title : Effects of ketoconazole and quinidine on pharmacokinetics of pactimibe and its plasma metabolite, R-125528, in humans.

Pub. Date : 2008 Aug

PMID : 18448569






1 Functional Relationships(s)
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1 Moreover, the f(m CYP2D6) of R-125528 estimated to be almost 1 would well explain the accumulation of R-125528 observed with the quinidine treatment. Quinidine cytochrome P450 family 2 subfamily D member 6 Homo sapiens