Pub. Date : 2008 Mar
PMID : 18444515
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, the fate of quinidine, a P-gp substrate, in the gastrointestinal tract after oral administration was examined in conscious rats. | Quinidine | phosphoglycolate phosphatase | Rattus norvegicus |
| 2 | In conclusion, this study has demonstrated that compounds with high solubility and high permeability, such as quinidine, can be absorbed rapidly at the proximal intestine,escaping the barrier function of P-gp, because P-gp is mostly expressed in the distal intestine. | Quinidine | phosphoglycolate phosphatase | Rattus norvegicus |
| 3 | In conclusion, this study has demonstrated that compounds with high solubility and high permeability, such as quinidine, can be absorbed rapidly at the proximal intestine,escaping the barrier function of P-gp, because P-gp is mostly expressed in the distal intestine. | Quinidine | phosphoglycolate phosphatase | Rattus norvegicus |