Title : Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.

Pub. Date : 2008 May

PMID : 18443590






1 Functional Relationships(s)
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1 Specifically, we found that cis variation at Ephx2 segregated with heart failure and with increased transcript expression, protein expression and enzyme activity, leading to a more rapid hydrolysis of cardioprotective epoxyeicosatrienoic acids. epoxyeicosatrienoic acids epoxide hydrolase 2 Rattus norvegicus