Title : Effects of scutellarin on apoptosis induced by cobalt chloride in PC12 cells.

Pub. Date : 2007 Dec 31

PMID : 18442013






1 Functional Relationships(s)
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1 These results demonstrate that scutellarin can protect PC12 cells from cobalt chloride induced apoptosis by scavenging ROS, inhibiting p38 phosphorylation, up-regulating Bcl-XL expression and decreasing caspase-3 activity, and may reduce the cellular damage in pathological conditions associated with hypoxia-mediated neuronal injury. scutellarin caspase 3 Rattus norvegicus