Title : Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress.

Pub. Date : 2008 Jun

PMID : 18441204






1 Functional Relationships(s)
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1 The HNP-induced COX-2 and ET-1 production was attenuated by the treatment with the oxygen free radical scavenger N-acetyl-L-cysteine and the inhibitors of p38 MAPK and NF-kappaB, respectively. Oxygen mitochondrially encoded cytochrome c oxidase II Homo sapiens