Title : DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.

Pub. Date : 2008 Apr 29

PMID : 18434539






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 p53 is activated in normal cells starved for pyrimidine nucleotides by treatment with N-(phosphonacetyl)-l-aspartate (PALA). sparfosic acid tumor protein p53 Homo sapiens