Title : Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease.

Pub. Date : 2008 May 15

PMID : 18430781






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huntington disease (HD) is caused by a polyglutamine-expansion mutation in huntingtin (HTT) that makes the protein toxic and aggregate-prone. polyglutamine huntingtin Drosophila melanogaster
2 Huntington disease (HD) is caused by a polyglutamine-expansion mutation in huntingtin (HTT) that makes the protein toxic and aggregate-prone. polyglutamine huntingtin Drosophila melanogaster