Title : The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.

Pub. Date : 2008 Oct

PMID : 18412143






1 Functional Relationships(s)
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1 These results support a notion that ROS-mediated activations of p38 MAPK and JNK in response to As2O3 treatment signals activation of Bax and phosphorylation of Bcl-2, resulting in mitochondrial apoptotic cell death in human cervical cancer cells. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens