Title : X-linked muscular atrophy and the androgen receptor.

Pub. Date : 1994 Dec

PMID : 18407238






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The resulting androgen receptor (AR) protein has an expanded polyglutamine tract in its NH(2)-terminal modulatory domain, and is postulated to lose a basic, intrinsic function that causes a mild form of androgen insensitivity; however, almost certainly, it also gains a novel, extrinsic function that is selectively neuronotoxic. polyglutamine androgen receptor Homo sapiens
2 The resulting androgen receptor (AR) protein has an expanded polyglutamine tract in its NH(2)-terminal modulatory domain, and is postulated to lose a basic, intrinsic function that causes a mild form of androgen insensitivity; however, almost certainly, it also gains a novel, extrinsic function that is selectively neuronotoxic. polyglutamine androgen receptor Homo sapiens