Title : P-glycoprotein function and expression during obstructive cholestasis in rats.

Pub. Date : 2008 May

PMID : 18403942






2 Functional Relationships(s)
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1 OBJECTIVES: The present study was aimed at evaluation of in vivo biliary and renal excretion of rhodamine 123 (Rho123), a P-glycoprotein (P-gp) substrate, in rats during either acute or chronic cholestasis induced by bile duct obstruction (BDO). Rhodamines ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
2 OBJECTIVES: The present study was aimed at evaluation of in vivo biliary and renal excretion of rhodamine 123 (Rho123), a P-glycoprotein (P-gp) substrate, in rats during either acute or chronic cholestasis induced by bile duct obstruction (BDO). Rhodamines ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus