Title : Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species.

Pub. Date : 2008 Jul

PMID : 18403484






1 Functional Relationships(s)
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1 Interestingly, dexamethasone induces the generation of reactive oxygen species (measured by dihydrofluorescein assay), which participate in the signaling process by triggering JNK activation. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens