Pub. Date : 2008 Jun
PMID : 18390821
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In lean pigs, capsaicin, a TRPV1 agonist, relaxed arteries in a dose-dependent manner (EC50 = 116 +/- 41 nM). | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Sus scrofa |
2 | Capsaicin-induced relaxation was blocked by the TRPV1 antagonist capsazepine, endothelial denudation, inhibition of nitric oxide synthase, and K+ channel antagonists. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Sus scrofa |
3 | Impaired capsaicin-induced vasodilation in the metabolic syndrome is associated with decreased expression of TRPV1 and cation influx. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Sus scrofa |