Title : Appearance and propagation of polyglutamine-based amyloids in yeast: tyrosine residues enable polymer fragmentation.

Pub. Date : 2008 May 30

PMID : 18381282






1 Functional Relationships(s)
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1 The presence of tyrosines within polyglutamine stretches dramatically enhanced polymer fragmentation and allowed polymer propagation in the absence of Rnq1 and, in some cases, of Hsp104. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C