Title : Mitochondrial lactate oxidation complex and an adaptive role for lactate production.

Pub. Date : 2008 Mar

PMID : 18379211






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Lactate is capable of upregulating MCT1 and COX gene and protein expression. Lactic Acid solute carrier family 16 member 1 Homo sapiens
2 Current findings allow us to understand how lactate production during exercise represents a physiological signal for the activation of a vast transcription network affecting MCT1 protein expression and mitochondrial biogenesis, thereby explaining how training increases the capacity for lactate clearance via oxidation. Lactic Acid solute carrier family 16 member 1 Homo sapiens
3 Current findings allow us to understand how lactate production during exercise represents a physiological signal for the activation of a vast transcription network affecting MCT1 protein expression and mitochondrial biogenesis, thereby explaining how training increases the capacity for lactate clearance via oxidation. Lactic Acid solute carrier family 16 member 1 Homo sapiens