Title : Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.

Pub. Date : 2008 Jul

PMID : 18378570






1 Functional Relationships(s)
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1 RESULTS: These studies showed that simvastatin blocks diabetes or high-glucose-induced increases in VEGF and ICAM-1 and preserves the BRB by a process involving blockade of diabetes/high-glucose-induced activation of STAT3 and NADPH oxidase. Simvastatin intercellular adhesion molecule 1 Homo sapiens