Title : Promotion of osteogenesis through beta-catenin signaling by desferrioxamine.

Pub. Date : 2008 May 30

PMID : 18375202






3 Functional Relationships(s)
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1 In BMP2-treated MSCs, desferrioxamine levels of 15 microMu were found to increase alkaline phosphatase (ALP) activity and calcium deposition, which were the markers of osteoblastic differentiation. Deferoxamine alkaline phosphatase, placental Homo sapiens
2 In BMP2-treated MSCs, desferrioxamine levels of 15 microMu were found to increase alkaline phosphatase (ALP) activity and calcium deposition, which were the markers of osteoblastic differentiation. Deferoxamine alkaline phosphatase, placental Homo sapiens
3 Knockdown of beta-catenin by RNA interference eliminates this positive effect of desferrioxamine on ALP activity. Deferoxamine alkaline phosphatase, placental Homo sapiens