Pub. Date : 2008 Jul 17
PMID : 18372923
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that alpha-TOS inhibits succinate dehydrogenase (SDH) activity of complex II (CII) by interacting with the proximal and distal ubiquinone (UbQ)-binding site (Q(P) and Q(D), respectively). | Ubiquinone | aminoadipate-semialdehyde synthase | Mus musculus |
| 2 | Here, we show that alpha-TOS inhibits succinate dehydrogenase (SDH) activity of complex II (CII) by interacting with the proximal and distal ubiquinone (UbQ)-binding site (Q(P) and Q(D), respectively). | Ubiquinone | aminoadipate-semialdehyde synthase | Mus musculus |
| 3 | We propose that alpha-TOS displaces UbQ in CII causing electrons generated by SDH to recombine with molecular oxygen to yield ROS. | Ubiquinone | aminoadipate-semialdehyde synthase | Mus musculus |