Pub. Date : 1991 Dec 11
PMID : 1837236
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Modification of the proteins with phenylglyoxal, an arginine-specific reagent, resulted in the loss of Type 1 IL-1 receptor binding activity. | Phenylglyoxal | interleukin 1 alpha | Homo sapiens |
2 | Cyanogen bromide cleavage of phenylglyoxal modified IL-1 alpha and IL-1 beta, followed by sequencing of the peptides, revealed that arginine-12 in IL-1 alpha and arginine-4 in IL-1 beta, which occupy the same topology in the respective crystallographic structures, are the target of phenylglyoxal. | Phenylglyoxal | interleukin 1 alpha | Homo sapiens |
3 | Cyanogen bromide cleavage of phenylglyoxal modified IL-1 alpha and IL-1 beta, followed by sequencing of the peptides, revealed that arginine-12 in IL-1 alpha and arginine-4 in IL-1 beta, which occupy the same topology in the respective crystallographic structures, are the target of phenylglyoxal. | Phenylglyoxal | interleukin 1 alpha | Homo sapiens |
4 | Cyanogen bromide cleavage of phenylglyoxal modified IL-1 alpha and IL-1 beta, followed by sequencing of the peptides, revealed that arginine-12 in IL-1 alpha and arginine-4 in IL-1 beta, which occupy the same topology in the respective crystallographic structures, are the target of phenylglyoxal. | Phenylglyoxal | interleukin 1 alpha | Homo sapiens |