Title : Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation.

Pub. Date : 2008 Feb 7

PMID : 18371437






1 Functional Relationships(s)
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1 In demethylated mutant mES cells, we saw upregulation of a subset of X-linked genes and developmental genes that are methylated in wild-type mES cells, but lack either H3K4 and H3K27 trimethylation or association with Polycomb, Oct4, or Nanog. 2-(N-morpholino)ethanesulfonic acid Nanog homeobox Mus musculus