Title : Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: development of in vitro high-speed screening systems.

Pub. Date : 2008 Mar

PMID : 18363541






2 Functional Relationships(s)
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1 OBJECTIVE: As the human ATP-binding cassette (ABC) transporter ABCG2 has been suggested to be critically involved in porphyrin-mediated photosensitivity, we aimed to develop in vitro screening systems for drug-induced phototoxicity. Porphyrins ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens
2 OBJECTIVE: As the human ATP-binding cassette (ABC) transporter ABCG2 has been suggested to be critically involved in porphyrin-mediated photosensitivity, we aimed to develop in vitro screening systems for drug-induced phototoxicity. Porphyrins ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens